Specular Microscopy Ancillary Study Methods for Donor Endothelial Cell Density Determination of Cornea Donor Study Images

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Donor age and corneal endothelial cell loss 5 years after successful corneal transplantation. Specular microscopy ancillary study results.

OBJECTIVE To determine whether endothelial cell loss 5 years after successful corneal transplantation is related to the age of the donor. DESIGN Multicenter, prospective, double-masked clinical trial. PARTICIPANTS Three hundred forty-seven subjects participating in the Cornea Donor Study who had not experienced graft failure 5 years after corneal transplantation for a moderate-risk conditio...

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Donor and recipient endothelial cell population of the transplanted human cornea: a two-dimensional imaging study.

Purpose. To elucidate the pattern of donor and recipient endothelial cell populations in transplanted human corneas and determine the degree to which donor endothelial cells survive in the graft. Methods. Thirty-six corneal grafts were collected from recipients of opposite sex to the donor, at the time of retransplantation for various indications. Cells from the endothelial side of the grafts w...

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Donor cell density and endothelial keratoplasty.

http://bjo.bmj.com/content/95/2/292.full.html Updated information and services can be found at: These include: References http://bjo.bmj.com/content/95/2/292.full.html#ref-list-1 This article cites 4 articles, 1 of which can be accessed free at: service Email alerting box at the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in the...

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Comparison of manual & automated analysis methods for corneal endothelial cell density measurements by specular microscopy.

PURPOSE To determine the reliability of corneal endothelial cell density (ECD) obtained by automated specular microscopy versus that of validated manual methods and factors that predict such reliability. METHODS Sharp central images from 94 control and 106 glaucomatous eyes were captured with Konan specular microscope NSP-9900. All images were analyzed by trained graders using Konan CellChek ...

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Donor risk factors for graft failure in the cornea donor study.

PURPOSE The purpose of this study was to assess the relationship between donor factors and 5-year corneal graft survival in the Cornea Donor Study. METHODS Donor corneas met criteria established by the Eye Bank Association of America, had an endothelial cell density of 2300 to 3300/mm, and were determined to be of good to excellent quality by the eye banks. Donor corneas were assigned using a...

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ژورنال

عنوان ژورنال: Current Eye Research

سال: 2006

ISSN: 0271-3683,1460-2202

DOI: 10.1080/02713680500536738